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The Advanced Light Source (ALS)

is located at Lawrence Berkeley National Laboratory, University of California at Berkeley in Berkeley, CA

ALS Structural Biology Beamlines Overview

xtal beamlines
Operational (general use)
Expts.
Wavelength (Å)
Yes
MAD and Monochromatic
0.5 - 3.5
yes
Monochromatic
0.97
yes
MAD & Monochromatic
0.82 - 3.1
yes
Monochromatic
1.0
yes
MAD
0.6 - 2.4
yes
MAD
0.6 - 2.4
yes
MAD
0.73 - 2.5
other bio beamlines
Operational (general use)
Expts.
Wavelength (Å)
12.3.1
yes
MAD/SAXS
0.72 - 4.0

About Structural Biology at ALS

PRTs (participating research teams, groups of researchers from one or more institutions) construct and operate beamlines at ALS and have primary responsibility for experiment endstation equipment. They are entitled to a percentage of the beamline's operating time based on the resources the PRT contributed to the beamline.

A national user facility serving over 750 scientists, representing 160 different research groups. The Center has five beamlines optimized for macromolecular protein crystallography (5.0.1, 5.0.2, 5.0.3, 8.2.1 and 8.2.2)

A consortium of academic institutions whose molecular biologists require macromolecular crystallographic information for their research. MBC operates beamline 4.2.2

Our LBL X-ray beamline (12.3.1) is called Sibyls - for Structurally-Integrated BiologY for Life Sciences. The Sibyls misssion is high-impact insights, not high throughput numbers.


Structural Genomics at ALS

The Center pursues an integrated structural genomics program designed to obtain a near-complete structural complement of two minimal genomes, Mycoplasma genitalium and Mycoplasma pneumoniae, two related human and animal pathogens.

A world-wide consortium of scientists developing a foundation for tuberculosis diagnosis and treatment by determining the 3-dimensional structures of proteins from M. tuberculosis.

Developing high throughput methods for target selection, cloning, expression, crystallization, X-ray diffraction, and structure determination.

Last Updated: May 14 2007

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